Effects of Green Alga, Chaetomorpha aerea Extract on Non-Specific Immune Responses and Disease Resistance against Edwardsiella tarda Infection in Labeo rohita

The current study evaluated the effects of a methanol extract from Chaetomorpha aerea (a green alga) on non-specific immune responses and resistance against Edwardsiella tarda infection in Labeo rohita. Different doses (5, 50 500 mg/kg body weight) were injected into fish intraperitoneally while control group was with 0.2 mL sterile physiological salt solution. Variations several immunostimulatory parameters (i.e., neutrophil, serum lysozyme, myeloperoxidase, antiprotease, ceruloplasmin activity), reactive oxygen species (ROS) nitrogen (RNS) assessed after 7, 14, 21, 28 days post stimulation. E. culture stimulation to induce monitor mortality within 14 days. Interestingly, all methanolic enhanced myeloperoxidase activity, ROS RNS, dose most effective. Fish this optimal also protected virulent strain tarda. results suggest that C. is potential prophylactic agent bacterial infections finfish.